Biochemistry

AU480 Clinical Chemistry System
The AU480 Clinical Chemistry System is a fully automated, computer-controlled clinical chemistry analyzer designed for the in vitro determination of a variety of general chemistries, electrolytes, proteins, therapeutic drugs, drugs of abuse and other chemistries. It can perform up to 400 photometric tests per hour (up to 800 with electrolytes), increased onboard testing, reduced sample volume and user-friendly operation.

More than 120 different Beckman Coulter System reagent applications are available including Serum Indices, specially designed to match the requirements and features of the new analyzer platform. The reagents are bar-coded, in addition with 2-D master calibration curves. Guaranteed standardization of results with the implementation of Universal applications "One Application fits all for all AU systems".

The system has twin sampling capability via rack loading or a cooled STAT turntable module. The sample rack feeder can hold up to 80 primary and secondary tubes in parallel. Different tube sizes may be mixed within the racks and can be loaded continuously. The STAT module provides quick emergency testing, on-board calibrator and QC storage for system access during auto calibration and auto QC. New state of the art sample and reagent volumes have been reached. Sample volumes as low as 1 µl, ideal for paediatric testing and reaction volumes down to as low as 90 µl guarantees cost efficiency. Computer controlled sample- and reagent dispensing based on CAN* technology in combination with clot detection and crash prevention are additional safety features which result in unique system reliability. The system security is further improved by context sensitive help screens and videos.

The AU480 Chemistry System has a new intuitive Graphic user interface, standardized to the AU680 minimizing any training requirements. A new ergonomically designed swing arm with a user friendly touch screen monitor is now available. User definable software options such as auto rerun via rack handler / STAT wheel and true reflex testing expand the convenience for the user. Automated low level maintenance requiring minimum hands-on time by the operator. TheAU480 Chemistry System uses dry bath technology therefore requiring no water bath maintenance. Low consumable replacement for example permanent cuvettes, long life electrodes (guaranteed for 6 months), robust sample and reagent probes.

The AU480 Chemistry System combines versatile advanced functions that facilitate high quality testing, improve turnaround time and cut operating costs. To minimize training requirements and assure safe handling by inexperienced staff, we emphasized ‘Easy to Use’ in developing the analyzer.

TheAU480 Chemistry System will continue to live up to the Beckman Coulter reputation of being the analyzer that is "reliable and precise"

Product Features :

 
 

Improved convenience

  • New and intuitive graphical user interface
  • Embedded maintenance videos
  • Universal applications
  • Plug and play calibration via 2-D barcode

Efficiency

  • Reagent reduction
  • Low consumable usage
  • Micro sampling ideal for pediatrics

Continuous loading sample feeder

  • Positive sample identification
  • Beckman Coulter flexible racks to handle all commonly used tube sizes in parallel
  • Bar-coded racks to define different sample materials
  • 80 samples on board at any time
  • Automatic repeat and reflex capability

Flexible STAT rotor

  • Dedicated STAT rotor with 22 positions and integrated barcode reader
  • Full STAT capabilities during routine operation
  • Refrigerated area for calibrators and controls
  • Combined routine and emergency work area

Large reagent compartment

  • 76 refrigerated reagent compartments
  • Ready to use liquid stable reagents
  • Automatic bottle switch capabilities
  • Advanced calibration
  • Liquid detection and remaining test number calculation

Cuvette wheel with low maintenance

  • Non disposable quartz cuvettes
  • Software driven carry over elimination
  • Dry incubation bath
  • Environmental friendly

Best in class ISE

  • High quality ISE for Na, K and Cl
  • 6 months shelf life
  • 18 months shelf life for reference electrodes
  • 600 tests/hour (if ISE mode only)
  • Same technology across the whole range of analyzers

Specifications :

 
Analytical system Fully automated, random access chemistry system with STAT capability
Analytical principle Spectrophotometry and potentiometry
Analytical types > Endpoint, rate, fixed point and indirect ISE
Analytical methods Colorimetry, turbidimetry, latex agglutination, homogeneous EIA, indirect ISE
Simultaneously processed analytes 60 photometric tests + 3 ISE, 120 pre-programmed onboard tests
Throughput 400 photometric tests/hour; maximum of 800 with ISE
ISE throughput 200 samples/hr.Maximum test/hr 600 if ISE only
Sample types Serum, plasma, urine, other
Sample feeder Racks with 10 samples each (barcodes on primary tubes and on racks); capacity of 80 samples; continuous loading
Sample tubes Primary and secondary tubes; diameter from 11.5 to 16 mm; height from 55 to 102 mm, nestled micro sample cups
STAT samples Up to 22 positions for STAT samples via cooled turntable. Easy to operate interrupts between tests Auto repeat run capability
Sample volume 1–25 μl in 0.1 μl steps (1–25 μl for repeats)
Reagent capacity 76 positions for (R1+R2, detergent position). Holds 15, 30 and 60ml bottles
Reagent storage Refrigerated (4 °C–12 °C )
Reagent volume R1: 10–250 μl; R2: 10–250 μl; (in 1 μl increment)
Total reaction volume 90–350 μl
Reaction cuvette Permanent glass cuvettes
Reaction time Up to 8 minutes, 37.5 seconds
Reaction incubation 37 °C, dry bath
Photometry system Direct assay through the reaction cuvette (0 – 3.0 OD) mono and bichromatic measurements possible
Wavelength 13 different wavelengths between 340 – 800 nm
Calibration Auto calibration, cooled calibrator positions; master calibration established by two-dimensional barcode
Quality control Auto QC, cooled QC positions
Rerun Auto QC, cooled QC positions
Sample Pre Dilution Dilution ratio: Fixed to 3, 5, 10, 15, 20, 25, 50, 76 or 100
Test requisition Individual and profile test requisition via on-line, mouse, function keys and touch screen
Sample integrity Lipaemia, Haemolysis and Icterus analysis. Sample clot detection and probe crash protection
Online RS232C. Full uni- and bidirectional communication possible
Software Windows XP®
Data Storage Sample number 100,000 samples. Reaction Data 200,000 tests
Dimensions (W x H x D) mm ANL: 1,450 x 1,205 x 760
Power supply 100–240v; 60 Hz/ < 3.5 kVA